Análisis de cumplimentación de las recetas médicas en soporte papel / Analysis of completion of medical prescriptions on paper

Dentro de las políticas farmacéuticas, el Estado se ha interesado por la receta médica como documento legal de prescripción y de dispensación de medicamentos y productos sanitarios, contribuyendo a la mejora en la seguridad del paciente. Con el objetivo de medir la cumplimentación de las recetas que llegan a la farmacia comunitaria se realizó un estudio observacional transversal, durante dos meses de 2019, revisando todas las recetas en soporte papel presentadas para su dispensación en cinco farmacias. En ese intervalo se recibieron un total de 33.463 recetas, 30.085 (89,90 %) eran electrónicas y 3.378 (10,10 %) en papel. De estas, 841 (25 %) eran del Sistema Nacional de Salud (SNS), 931 (27 %) de MUFACE, 362 (11 %) de ISFAS, 28 (1 %) de MUGEJU, 201 (6 %) de otras mutuas y 1.015 (30 %) de asistencia sanitaria privada. Cuando se analizó el número y porcentaje de recetas en papel que podían ser dispensadas legalmente, se observó que sólo 130 (65 %) recetas de otras mutuas, 30 (4 %) recetas del SNS y 34 (3 %) recetas privadas estaban correctamente cumplimentadas. Por tanto, sólo 194 de las 3.378 recetas en papel analizadas (6 %) que se han recibido durante dos meses en las cinco farmacias podían ser dispensadas de acuerdo con la ley actual. Cuando las recetas no están correctamente cumplimentadas, con los datos básicos obligatorios, indispensables para la validez de la receta médica, la seguridad del paciente puede verse comprometida y los profesionales sanitarios que prescriben y los que dispensan los medicamentos se exponen a sanciones

Within the pharmaceutical policies, the State has been interested in the medical prescription as a legal document of prescription and dispensing medicines and health products contributing to the improvement in patient safety. To measure the degree of compliance of the prescriptions that arrive at the community pharmacy, a cross-sectional observational study was conducted for two months of 2019 to review all the prescriptions on paper presented for dispensing in five pharmacies. Within this period, a total of 33463 prescriptions were received 30085 (89.90%) were electronic and 3378 (10.10%) were on paper. Of these, 841 (25%) came from the public health system, 931 (27%) from MUFACE, 362 (11%) from ISFAS, 28 (1%) from MUGEJU, 201 (6%) other organizations and 1015 (30%) from private healthcare. When the number and percentage of paper prescriptions that could be legally dispensed was analysed, it was observed that only 130 (65%) prescriptions of other organizations, 30 (4%) of the public health system and 34 (3%) of private healthcare were correctly completed. Therefore, only 194 of the 3,378 paper prescriptions (6%) received during two months in the five community pharmacies could be dispensed according to current law. When the prescriptions are not correctly filled, with the mandatory basic data, indispensable for the validity of the medical prescription, the patient's safety can be compromised and the prescribing health professionals and those who dispense the medications are exposed to sanctions

Factor H and CFHR1 polymorphisms associated with atypical Haemolytic Uraemic Syndrome (aHUS) are differently expressed in Tunisian and in Caucasian populations.

Several polymorphisms in the complement components factor H and CFHR1 are associated with higher risk to develop atypical Haemolytic Uraemic Syndrome (aHUS) in Caucasians. We have determined the prevalence of these polymorphisms in Tunisian controls by using genetic and immunological techniques. No differences in the frequency of the factor H risk alleles c.-331C>T, c.2089A>G or c.2881G>T between Tunisian and Caucasians were found. On the contrary, the analysis of CFHR1 polymorphism revealed a higher frequency of Tunisian individuals homozygous for the CFHR1*Del (deleted) allele, and of individuals presenting the CFHR1*A phenotype. These results suggest distinct contributions of factor H and CFHR1 polymorphisms to aHUS in Tunisian and Caucasian populations.